Publications

Available online

  1. Gartlgruber, M, Sharma, AK , Quintero, A, Dreidax, D, Jansky, S, Park, Y, Gogolin, S, Meder, J, Doncevic D, Saary P, Toprak, UH, Ishaque, N, Afanasyeva, E, Koster, J, Versteeg R, Grünewald, TGP, Jones, DTW, Pfister, SM, Henrich, K, Nes, Jv, Herrmann, C, Westermann, F. Super enhancers define regulatory subtypes and cell identity in neuroblastoma. Nature Cancer (2020)

  2. Jansky S, Sharma AK , Körber V, Toprak UH, Gartlgruber M, Greco A, Quintero A, Chomsky E, Henrich K, Tanay A, Herrmann C, Höfer T, Westermann F. Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma. Nature Genetics (2021)

  3. Alvarez CR, Kee C, Sharma AK , Thomas L, Schmidt F, Stanifer ML, Boulant S, Herrmann C. SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity bioRxiv (2021)

  4. Afanasyeva EA, Gartlgruber M, Ryl T, Decaesteker B, Denecker G, Mönke G, Toprak UH, Florez A, Torkov A, Dreidax D, Herrmann C, Okonechnikov K, Sharma, AK, Sagulenko V, Speleman F, .Henrich KO, Westermann, F. Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma. Life science alliance (2021)

  5. Triana S, Metz Zumaran C, Ramirez C, Kee C, Doldan P, Shahraz M, Schraivogel D, Gschwind AR, Sharma AK, Steinmetz LM, Herrmann C. Single cell analyses reveal SARSCoV2 interference with intrinsic immune response in the human gut. Molecular systems biology (2021)

  6. Schwarz E, Alnæs D, Andreassen OA, Cao H, Chen J, Degenhardt F, Dwyer D, Eils R, Erdmann J, Herrmann C, Hofmann-Apitius M, Kaufmann T, Koutsouleris N, Kodamullil AT, Khuntia A, Munoz-Venegas ML, Nöthen MM, Paul R, Quintero A, Schunkert H, Sharma AK, Tost H, Westlye LT, Zhang Y, Meyer-Lindenberg A Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap. Molecular Psychiatry (2020

  7. Ansari, SS, Sharma, AK, Ali,D, Eibl, H, Soni, H, Tews, B, König, R, Berger, MR. Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells. Cell Death and Disease (2018)

  8. Ansari, S. S., Sharma, AK, Zepp, M., Ivanova, E., Bergmann, F., König, R., Berger, M. R. Upregulation of cell cycle genes in head and neck cancer patients may be antagonized by erufosine’s down regulation of cell cycle processes in OSCC cells. Oncotarget (2017)

  9. Sharma AK, Eils R and König R. Copy number alterations in enzyme-coding and cancer-causing genes reprogram tumor metabolism. Cancer Research (2016)

  10. Sharma AK Computational Analysis of Metabolic Reprogramming in Tumors. Doctoral Dissertation, (2016)

  11. Shukla K, Sharma AK, Ward A, Will R, Hielscher T, Balwierz A, Breunig C, Münstermann E, König R, Keklikoglou I and Wiemann S. MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Molecular Oncology (2015)

  12. Khandelwal N, Breinig M, Speck T, Michels T, Kreutzer C, Sorrentino A, Sharma AK, Umansky L, Conrad H, Poschke I, Offringa R, König R, Bernhard H, Machlenkin A, Boutros M and Beckhove P. A high-throughput RNAi screen for detection of immune checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes. EMBO Molecular Medicine (2015)

  13. Ummanni R, Mannsperger HA, Sonntag J, Oswald M, Sharma AK, König R, Korf U. Evaluation of reverse phase protein array (RPPA)–based pathway activation profiling in 84 non–small cell lung cancer (NSCLC) cell lines as platform for cancer proteomics and biomarker discovery. Biochimica et Biophysica Acta (BBA)–Proteins and Proteomics (2014)

  14. Sharma AK and König R. Metabolic network modeling approaches for investigating the “hungry cancer”. Seminars in Cancer Biology (2013)

IN PREPARATION

  1. Sharma AK et.al, Integrative modelling of directed networks of epigenetic regulation across human tissues. (2021)